内皮祖细胞与慢性阻塞性肺疾病：从基础研究到临床应用
雪 何, 慧卉 曾, 燕 陈 · 2024
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Description
Xue He and co-authors review endothelial progenitor cells, the body's vessel repair crew, and their faltering role in chronic lung disease. COPD scars airways and also rots the vessel lining, a twin hit this review centers. Repair cells that could patch that lining run low and weak in patients.
Counts and vigor of these cells track disease severity, lung decline, flare-ups, and nutrition state. Smoke, vaping, nicotine, and fine particles each wound the repair crew further. Two signaling highways and several cytokine dials govern how the cells mobilize and home. In animal work, piping the cells into emphysema lungs lifts function and tissue looks. The authors weigh what must be proven before cell therapy earns a clinic place: dosing, safety, and staying power all stay open.
Catalog record
| CREATOR | 雪 何, 慧卉 曾, 燕 陈 |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 14 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |