Tailored chiral phosphoramidites support highly enantioselective Pd catalysts for asymmetric aminoalkylative amination
Suchen Zou, Zeyu Zhao, Guoqing Yang, Hanmin Huang · 2024
Read Tailored chiral phosphoramidites support highly enantioselective Pd catalysts for asymmetric aminoalkylative amination by Suchen Zou, Zeyu Zhao, Guoqing Yang, Hanmin Huang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11612159.txt.
Description
Suchen Zou, Zeyu Zhao, Guoqing Yang, and Hanmin Huang tune the distant charge of a helper ligand to make a ring-closing build land one hand form near pure. The build joins two nitrogen parts in one step to give ring products with an allene arm. Their 2024 find is that a distant CN swap on the frame of the helper bends the span of the key bond in the middle step, which sets the hand choice.
With that helper, a wide set of ring nitrogen products came out at up to past 99 percent hand purity. A one-pot twin step then ran the build and a next join in line to give twin-core products fast. Distant charge, long held a weak dial, proves a keen one here.
Catalog record
| CREATOR | Suchen Zou, Zeyu Zhao, Guoqing Yang, Hanmin Huang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |