Gellan gum-based granular gels as suspension media for biofabrication

Andrew McCormack, Laura M. Porcza, Nicholas R. Leslie, Ferry P. W. Melchels, Pradeep Kumar, Pradeep Kumar, Pradeep Kumar · 2024

Read Gellan gum-based granular gels as suspension media for biofabrication by Andrew McCormack, Laura M. Porcza, Nicholas R. Leslie, Ferry P. W. Melchels, Pradeep Kumar, Pradeep Kumar, Pradeep Kumar (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11602023.txt.

Description

Andrew McCormack and co-authors present in 2024 a grainy gel that can hold soft printed structures while they set. Building tissue-like constructs in three dimensions is a standing challenge in medicine. A new trick prints watery inks inside a support bath that flows around the print head, then holds firm. Their bath is made of gellan gum, sheared while it gels so it breaks into grains.

The grains give the bath a paste-like behavior across a wide heat range, from fridge cold to body warmth. Its resistance to flow is very low, which allowed print speeds up to sixty millimeters per second. The team printed droplets carrying live cells and kept them for seven days. They also built features inside a version of the bath that can itself set firm. Easy making, speed, and that setting option make it a strong candidate, they argue.

Catalog record

CREATORAndrew McCormack, Laura M. Porcza, Nicholas R. Leslie, Ferry P. W. Melchels, Pradeep Kumar, Pradeep Kumar, Pradeep Kumar
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE74 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11602023

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