High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
Xu H, Zhong L, Deng J et al. · 2020
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Description
Hao Xu, Li Zhong, Jia Deng, and coauthors studied ACE2 in the mouth early in the COVID-19 outbreak in 2020. ACE2 is the main door the new coronavirus uses to enter human cells. The team asked whether the mouth lining could be an entry route.
Using public RNA data, they found ACE2 strongly present on tongue and other oral lining cells. That presence hints the mouth may be an early infection site and a source of virus in saliva. The finding supported attention to oral spread and protection in dentistry. It was among the first clues that saliva testing could work.
Catalog record
| CREATOR | Xu H, Zhong L, Deng J et al. |
|---|---|
| YEAR | 2020 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PubMed Central |