OrthoFinder: phylogenetic orthology inference for comparative genomics
David M. Emms, Steven Kelly · 2019
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Description
David Emms and Steven Kelly presented a major advance of OrthoFinder in 2019. OrthoFinder sorts genes across species into groups descended from single ancestral genes. That sorting is the base step for most comparative genomics.
The new version goes further, building rooted gene trees and the species tree itself. It also calls gene duplication events and reports comparison statistics. Accuracy stays high while the scope widens greatly. Teams with a fresh set of genomes can now get a full first evolutionary analysis from one tool. The method scales to hundreds of species, which earlier orthology tools could not handle in reasonable time.
Catalog record
| CREATOR | David M. Emms, Steven Kelly |
|---|---|
| YEAR | 2019 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PubMed Central |