The Metabolic Signature of Macrophage Responses

Antonella Viola, Fabio Munari, Ricardo Sánchez-Rodríguez et al. · 2019

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Description

Antonella Viola, Fabio Munari, Ricardo Sánchez-Rodríguez, and coauthors reviewed macrophage metabolism in 2019. Macrophages are immune cells with many jobs, from eating germs to healing tissue. Their behavior depends on how they fuel themselves.

Different tasks call for different metabolic settings inside the cell. Inflammatory macrophages lean on fast sugar burning, while healing types favor slower, oxygen-based routes. The review maps these signatures and the signals that flip them. Reprogramming metabolism may one day steer macrophages in diseases from arthritis to cancer. The authors close by naming the metabolic questions that single-cell methods may soon answer.

Catalog record

CREATORAntonella Viola, Fabio Munari, Ricardo Sánchez-Rodríguez et al.
YEAR2019
COLLECTIONPAPERS
FORMATTXT
FILE SIZE96 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPubMed Central

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC6618143/

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