cytoHubba: identifying hub objects and sub-networks from complex interactome

Chin CH, Chen SH, Wu HH et al. · 2014

Read cytoHubba: identifying hub objects and sub-networks from complex interactome by Chin CH, Chen SH, Wu HH et al. (2014) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-4290687.txt.

Description

Chin, Chen, Wu, and their co-authors built cytoHubba in 2014 to find key nodes in biological networks. Networks display many kinds of data, from protein interactions to gene regulation and cell pathways. Scoring nodes by their network features can reveal which ones matter most.

CytoHubba ranks nodes and pulls out hub objects and dense sub-networks from a complex interactome. Hubs often hold a network together, so they are prime targets for study. The tool works inside the popular Cytoscape platform for network viewing. It helps researchers move from a hairball of links to a short list of genes or proteins worth testing in the lab.

Catalog record

CREATORChin CH, Chen SH, Wu HH et al.
YEAR2014
COLLECTIONPAPERS
FORMATTXT
FILE SIZE22 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPubMed Central

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4290687/

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