Trimmomatic: a flexible trimmer for Illumina sequence data

Bolger AM, Lohse M, Usadel B. · 2014

Read Trimmomatic: a flexible trimmer for Illumina sequence data by Bolger AM, Lohse M, Usadel B. (2014) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-4103590.txt.

Description

Bolger, Lohse, and Usadel introduced Trimmomatic in 2014, a tool that cleans raw sequencing reads. Before analysis, reads from Illumina machines often need trimming to remove adapter pieces and low-quality ends. Many tools existed, but the authors found none that met all their needs at once.

Trimmomatic was built to be flexible, fast, and correct with paired-end data, where two reads come from the same DNA piece. It chains trimming steps in the order the user chooses. Clean input reads improve every later step, from genome assembly to variant calling. The tool became a standard first pass in sequencing pipelines worldwide.

Catalog record

CREATORBolger AM, Lohse M, Usadel B.
YEAR2014
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPubMed Central

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC4103590/

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