The RIN: an RNA integrity number for assigning integrity values to RNA measurements
Andreas Schroeder, Odilo Mueller, Susanne Stocker et al. · 2006
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Description
Schroeder, Mueller, Stocker, and co-authors introduce the RIN, an RNA integrity number for grading RNA samples. RNA is fragile, and its quality decides whether a gene activity snapshot is trustworthy. Before their work, labs had no reliable standard score, relying on rough ratios from gel images.
The RIN gives each sample a single clear grade of how intact its RNA is. Labs can then drop poor samples before costly tests, or note quality limits when reporting results. A shared score made studies easier to compare and helped raise standards across gene expression research.
Catalog record
| CREATOR | Andreas Schroeder, Odilo Mueller, Susanne Stocker et al. |
|---|---|
| YEAR | 2006 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PubMed Central |