Antibody-associated responses are linked to increased susceptibility to Rhodococcus equi infection in mice
Yasunori Suzuki, Shusei Fujiwara, Makoto Sugiyama, Shinji Takai · 2026
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Description
Yasunori Suzuki and co-authors find that antibody-led immunity can worsen a lung germ's grip in mice, in this 2026 study. The germ hides inside the very cells meant to kill it, and foals suffer its pneumonia badly. Cell-led defense is thought to be the shield.
Shots of live germs guarded mice against later attack. Shots of killed germs or germ parts did the opposite, raising germ counts and deaths. Antibodies from those mice helped the germ grow inside cells in a dish. Live shots instead primed killer T cells. The authors warn vaccine design must favor the cell path over the antibody path.
Catalog record
| CREATOR | Yasunori Suzuki, Shusei Fujiwara, Makoto Sugiyama, Shinji Takai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |