Longitudinal and adjusted prognostic assessment of calprotectin in Gram-negative sepsis with acute respiratory failure
Simona Gigliotti, Michele Manno, Manuela Colosimo, Francesca Divenuto, Francesco Dragone, Marta Greco, Cinzia Peronace, Luigia Gallo, Francesca Trimboli, Pasquale Minchella, Francesca Greco, Alba Silipo, Nadia Marascio, Eugenio Garofalo, Federico Longhini, Angela Quirino, Giovanni Matera · 2026
Read Longitudinal and adjusted prognostic assessment of calprotectin in Gram-negative sepsis with acute respiratory failure by Simona Gigliotti, Michele Manno, Manuela Colosimo, Francesca Divenuto, Francesco Dragone, Marta Greco, Cinzia Peronace, Luigia Gallo, Francesca Trimboli, Pasquale Minchella, Francesca Greco, Alba Silipo, Nadia Marascio, Eugenio Garofalo, Federico Longhini, Angela Quirino, Giovanni Matera (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13689393.txt.
Description
Simona Gigliotti leads a seventeen-author team tracking a blood marker in severe sepsis, in a study published in two thousand twenty-six. The patients had Gram-negative bloodstream infections with acute respiratory failure. Calprotectin, released by activated immune cells, was the candidate prognostic signal.
Eighty-two adults across centers were followed for twenty-eight-day survival. Blood was sampled at diagnosis, day three, and day seven. Calprotectin fell over time in everyone but stayed higher in the eighteen patients who died. Levels differed significantly at every time point. The marker's trajectory, though, did not differ between groups. Routine biomarkers, cytokines, and growth factors were measured alongside. The study sizes up calprotectin's added prognostic value.
Catalog record
| CREATOR | Simona Gigliotti, Michele Manno, Manuela Colosimo, Francesca Divenuto, Francesco Dragone, Marta Greco, Cinzia Peronace, Luigia Gallo, Francesca Trimboli, Pasquale Minchella, Francesca Greco, Alba Silipo, Nadia Marascio, Eugenio Garofalo, Federico Longhini, Angela Quirino, Giovanni Matera |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |