In vitro evaluation of hydroxyapatite, β-tricalcium phosphate, graphene oxide and zinc oxide for osteochondral regeneration under inflammatory conditions
Roman Novotný, Izabella Rajzer, Jana Franková · 2026
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Description
Roman Novotny, Izabella Rajzer, and Jana Frankova test four materials for joint surface repair in a 2026 dish study. Such defects are hard to heal since bone and cartilage regrow at unlike rates, and long term swelling makes repair harder still.
Bone like and cartilage like cells were grown with a swelling trigger plus each material in turn. All four kept basic matrix making alive while muting enzymes that chew matrix up. One carbon sheet guarded cartilage cells best. A zinc compound, by contrast, trapped a key growth switch and blocked mineral build. The split argues for layered use, matched to each tissue.
Catalog record
| CREATOR | Roman Novotný, Izabella Rajzer, Jana Franková |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |