Joint ancestry inference reveals the landscape of archaic introgression in admixed populations
Jazeps Medina Tretmanis, Valeria Añorve-Garibay, David Peede, Mayra M. Bañuelos, María C. Ávila-Arcos, Flora Jay, Emilia Huerta-Sanchez · 2026
Read Joint ancestry inference reveals the landscape of archaic introgression in admixed populations by Jazeps Medina Tretmanis, Valeria Añorve-Garibay, David Peede, Mayra M. Bañuelos, María C. Ávila-Arcos, Flora Jay, Emilia Huerta-Sanchez (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13684439.txt.
Description
Jazeps Medina Tretmanis and co-authors build a deep learning tool that reads a person's genome and sorts each stretch by origin, in a 2026 study. For people of mixed ancestry, the tool must spot both recent continental roots and much older archaic roots, from early human cousins. Doing both at once is hard, and no earlier method managed it.
Their tool, TRACTINATOR, mixes gene variant data, population frequencies, and a known test statistic. Training on real plus synthetic data sharpened both tasks. Applied to Latin American genomes, it maps where archaic stretches sit inside African, European, and Indigenous American segments, and traces how some of them arrived.
Catalog record
| CREATOR | Jazeps Medina Tretmanis, Valeria Añorve-Garibay, David Peede, Mayra M. Bañuelos, María C. Ávila-Arcos, Flora Jay, Emilia Huerta-Sanchez |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |