FGFR3 mRNA expression in urothelial bladder cancer: Associations with tumor phenotype without prognostic impact
Kiril Pakovski, Marija Markova, Josif Janchulev, Martina Ambardjieva, Aleksandra Gavrilovska-Brzanov, Slavica Josifovska, Skender Saidi, Sasho Panov · 2026
Read FGFR3 mRNA expression in urothelial bladder cancer: Associations with tumor phenotype without prognostic impact by Kiril Pakovski, Marija Markova, Josif Janchulev, Martina Ambardjieva, Aleksandra Gavrilovska-Brzanov, Slavica Josifovska, Skender Saidi, Sasho Panov (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13682537.txt.
Description
Kiril Pakovski and co-authors measured how much FGFR3 message bladder tumors carry, and whether the level says anything about the cancer's behavior. FGFR3 is a growth receptor often altered in this cancer and linked to milder disease, but its value as a forecast tool was unclear. The team tested fresh tumor tissue from eighty patients.
Higher levels tracked strongly with cancers that had not invaded the muscle wall and with low tumor grade. Yet the levels did not predict overall survival, nor return of disease in the non-invasive group. Age and grade also carried no forecast value here. The authors say the measure may help describe a tumor at diagnosis, but larger studies must test any role in predicting outcomes.
Catalog record
| CREATOR | Kiril Pakovski, Marija Markova, Josif Janchulev, Martina Ambardjieva, Aleksandra Gavrilovska-Brzanov, Slavica Josifovska, Skender Saidi, Sasho Panov |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |