Numerous scattered clusters of submillimeter blue-gray and brown macules on the skin of a patient with progressive joint destruction

Graham Grisedale, Andrew Siref, Ryan Trowbridge · 2026

Read Numerous scattered clusters of submillimeter blue-gray and brown macules on the skin of a patient with progressive joint destruction by Graham Grisedale, Andrew Siref, Ryan Trowbridge (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13682470.txt.

Description

Graham Grisedale, Andrew Siref, and Ryan Trowbridge pose a skin puzzle tied to failing joints in a 2026 clinical image case. A man in his early forties came for a full skin check with clusters of tiny blue-gray and brown spots on his arms. His ear rims held gray patches too. He told of a decade of joint wear, worst in the hips.

The quiz offers five picks for the spots. The answer is ochronosis, the stain left by a rare gene flaw that lets a body chemical build up and darken soft tissues. Skin clues come first, the team notes, and a plain urine color test can seal the call.

Catalog record

CREATORGraham Grisedale, Andrew Siref, Ryan Trowbridge
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE4 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13682470

Browse the full library · About the Tower of Babel