Potential molecular links between triclosan exposure and osteoarthritis: An integrative systems toxicology study
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li · 2026
Read Potential molecular links between triclosan exposure and osteoarthritis: An integrative systems toxicology study by Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13682359.txt.
Description
Xijie Tang and co-authors probe how triclosan, a common antimicrobial, might feed joint damage in osteoarthritis, in this 2026 study. The chemical is known to stir oxidative and immune upset, but its molecular links to the disease were unclear. The team combined network toxicology, gene data, and cell tests.
Thirty candidate genes tied to both the chemical and the disease were found, and four were ranked top. One gene stood out for stable model weight and wide presence in joint cells. In rat joint cells, low-dose exposure raised oxidative stress and shifted the key genes. The authors frame a testable model for later work.
Catalog record
| CREATOR | Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |