Mitophagy coordinates organelle crosstalk in health and diseases
Mengyao Wu, Pengyi He, Yajun Lian, Tuo Zhang, Yiqi Wu, Lu Wang, Daolin Tang, Yongming Yao, Renqi Yao · 2026
Read Mitophagy coordinates organelle crosstalk in health and diseases by Mengyao Wu, Pengyi He, Yajun Lian, Tuo Zhang, Yiqi Wu, Lu Wang, Daolin Tang, Yongming Yao, Renqi Yao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13680487.txt.
Description
Mengyao Wu and co-authors review in 2026 how the cell's cleanup of worn-out mitochondria keeps its organelles talking to each other. That cleanup, mitophagy, removes damaged power plants before they poison the cell. The review argues it also steers the wider organelle web, from the protein-folding compartment to fat droplets.
Signals run both ways along contact sites and shared chemistry, shaping stress responses, redox balance, and cell fate. When the chatter breaks, organ function suffers across diseases. The authors close by surveying small molecules that tune mitophagy, as candidate tools to restore healthy organelle communication.
Catalog record
| CREATOR | Mengyao Wu, Pengyi He, Yajun Lian, Tuo Zhang, Yiqi Wu, Lu Wang, Daolin Tang, Yongming Yao, Renqi Yao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 191 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |