The brain of the female Anopheles gambiae mosquito at spatial and single-cell resolution

Irene Z Rossi, Cécile Cassan, Johannes W Bagnoli, Sümeyye Özhan, Adeline Valente, Quentin J Delorme, Geert-Jan van Gemert, Chiara Andolina, Wouter Graumans, Richárd Bártfai, Avinash R Shenoy, David Carrasco, Emmanuel Perisse, Teun Bousema, Sarah H Merkling, Anna Cohuet, Arthur M Talman · 2026

Read The brain of the female Anopheles gambiae mosquito at spatial and single-cell resolution by Irene Z Rossi, Cécile Cassan, Johannes W Bagnoli, Sümeyye Özhan, Adeline Valente, Quentin J Delorme, Geert-Jan van Gemert, Chiara Andolina, Wouter Graumans, Richárd Bártfai, Avinash R Shenoy, David Carrasco, Emmanuel Perisse, Teun Bousema, Sarah H Merkling, Anna Cohuet, Arthur M Talman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13680466.txt.

Description

Irene Rossi and a large team of colleagues build a cellular atlas of the female malaria mosquito's brain. Blood feeding by Anopheles gambiae starts every malaria infection, and behavior is orchestrated by the brain. Combining spatial mapping with single-cell RNA sequencing, they catalog the brain's cell diversity and compare it with other insects.

Rather than expanding particular cell populations after life events, the brain modulates neurotransmission when females mate. After a blood meal, glia, memory-related Kenyon cells, and immune cells mount metabolic and immune responses. Aging signatures also appear in the brain. Infection with the malaria parasite itself left no detected effect. The atlas is offered as a resource for studying vector behavior and transmission.

Catalog record

CREATORIrene Z Rossi, Cécile Cassan, Johannes W Bagnoli, Sümeyye Özhan, Adeline Valente, Quentin J Delorme, Geert-Jan van Gemert, Chiara Andolina, Wouter Graumans, Richárd Bártfai, Avinash R Shenoy, David Carrasco, Emmanuel Perisse, Teun Bousema, Sarah H Merkling, Anna Cohuet, Arthur M Talman
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE82 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13680466

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