Kidney involvement in idiopathic multicentric Castleman disease–TAFRO syndrome: clinical spectrum, pathology and outcomes
Shuo Zhang, Hanshu Liu, Siyuan Li, Yubing Wen, Wenling Ye, Wei Ye, Hua Zheng, Lubin Xu, Fei Teng, Ying Wang, Ke Zheng, Peng Xia, Lu Zhang, Jian Li, Xuemei Li, Limeng Chen · 2026
Read Kidney involvement in idiopathic multicentric Castleman disease–TAFRO syndrome: clinical spectrum, pathology and outcomes by Shuo Zhang, Hanshu Liu, Siyuan Li, Yubing Wen, Wenling Ye, Wei Ye, Hua Zheng, Lubin Xu, Fei Teng, Ying Wang, Ke Zheng, Peng Xia, Lu Zhang, Jian Li, Xuemei Li, Limeng Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13678736.txt.
Description
Shuo Zhang and co-authors chart how a rare immune disease attacks the kidneys. Their 2026 study covers a ten-year group of forty-eight patients at a Beijing hospital. All had the TAFRO form of idiopathic multicentric Castleman disease, an aggressive illness marked by swelling, low platelets, and organ growth.
Kidney involvement showed in nearly every patient, most often as scant urine, traces of blood and protein, and rising waste levels. Four in five of those patients suffered acute kidney injury, and over a third needed dialysis. Biopsies pointed to damage in the kidney's small vessels. Most patients recovered kidney function with firm disease treatment plus support, and dialysis patients survived no worse than the rest. Inflammation markers tracked the injury closely.
Catalog record
| CREATOR | Shuo Zhang, Hanshu Liu, Siyuan Li, Yubing Wen, Wenling Ye, Wei Ye, Hua Zheng, Lubin Xu, Fei Teng, Ying Wang, Ke Zheng, Peng Xia, Lu Zhang, Jian Li, Xuemei Li, Limeng Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |