Unsaturated fatty acids as immunometabolic modulators in high-risk pregnancies: mechanisms, clinical evidence, and translational perspectives
Edmarcio Olinto da Fonseca, Jocilda Carvalho de Faria, Regiane Penaforte Santos, Julia Vieira Carvalho, Caroline Maria Oliveira Volpe · 2026
Read Unsaturated fatty acids as immunometabolic modulators in high-risk pregnancies: mechanisms, clinical evidence, and translational perspectives by Edmarcio Olinto da Fonseca, Jocilda Carvalho de Faria, Regiane Penaforte Santos, Julia Vieira Carvalho, Caroline Maria Oliveira Volpe (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13678167.txt.
Description
Olinto da Fonseca and co-authors review unsaturated fats as immune-metabolic modulators in risky pregnancies. High-risk pregnancy mixes metabolic strain, low-grade inflammation, and placenta faults. Omega-3 fats like EPA and DHA reshape cell membranes. They damp NF-kB signals and inflammasome firing. They also aid mitochondria and yield pro-resolving mediators.
Clinical proof spans cohort studies, trials, and pooled analyses. Omega-3 intake links to lower preterm birth risk in the data. Gains look strongest in women with low baseline intake. The review maps mechanisms cell by cell. It weighs how fat intake could ease placenta inflammation.
Catalog record
| CREATOR | Edmarcio Olinto da Fonseca, Jocilda Carvalho de Faria, Regiane Penaforte Santos, Julia Vieira Carvalho, Caroline Maria Oliveira Volpe |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |