Refractory Anti‐HMGCR Necrotizing Myopathy With Progressive Hypercapnic Respiratory Failure Responsive to a JAK Inhibitor
N Huang, T B George, L Christopher-Stine, A Nicolas, C Oddis, D P Ascherman, V M Liarski, Ankit Dhoundiyal · 2026
Read Refractory Anti‐HMGCR Necrotizing Myopathy With Progressive Hypercapnic Respiratory Failure Responsive to a JAK Inhibitor by N Huang, T B George, L Christopher-Stine, A Nicolas, C Oddis, D P Ascherman, V M Liarski, Ankit Dhoundiyal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13678112.txt.
Description
Huang and co-authors report a hard case of muscle disease in a 73-year-old woman whose breathing failed as her muscles weakened, in a 2026 case report. Her illness, a rare immune attack on muscle often tied to statin drugs, had resisted many strong treatments over years. Weak breathing muscles can turn such a disease life-threatening.
Care in hospital with standard immune drugs did not stop the decline, and she needed a breathing machine. After a drug that blocks a key immune signal was added, she improved fast, left the machine, and went home breathing on her own. The authors urge trials of this drug class for similar stubborn cases.
Catalog record
| CREATOR | N Huang, T B George, L Christopher-Stine, A Nicolas, C Oddis, D P Ascherman, V M Liarski, Ankit Dhoundiyal |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |