Efficacy, safety, and strategy-modifying factors of pulsed field ablation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis
Yuanlin Zhou, Jianhua Xie, Mingliang Fang, Shipeng Wang, Xiaohong Bin, Qingyao Liao · 2026
Read Efficacy, safety, and strategy-modifying factors of pulsed field ablation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis by Yuanlin Zhou, Jianhua Xie, Mingliang Fang, Shipeng Wang, Xiaohong Bin, Qingyao Liao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13677292.txt.
Description
Yuanlin Zhou and five co-authors pool the evidence on pulsed field ablation for stubborn atrial fibrillation, in a paper dated 2026. The technique zaps heart tissue with electric pulses rather than heat, promising speed and safety near the esophagus. The hardest cases, persistent and long-standing fibrillation, had never had a dedicated synthesis.
The team searched five databases into 2026 and handled the literature's messiness carefully: only truly comparable head-to-head studies were pooled, while single studies were summarized and strategy questions explored with single-arm pooling. Extra lesion sets beyond the standard, such as the heart's back wall, were a key question. Outcomes off rhythm drugs counted most. The review gives electrophysiologists a graded map of what the new tool achieves in advanced disease.
Catalog record
| CREATOR | Yuanlin Zhou, Jianhua Xie, Mingliang Fang, Shipeng Wang, Xiaohong Bin, Qingyao Liao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |