Lipid dynamics shape thermogenic adaptation in brown fat during fasting

Wentong Jia · 2026

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Description

Wentong Jia wrote a commentary, published in 2026, on how brown fat handles fat during fasting. Brown fat is a special tissue that burns fuel to make heat. White fat, by contrast, mainly stores fuel. When an animal fasts, white fat breaks down and sends fatty fuel into the blood. Brown fat then takes up much of that fuel. What it does with the fuel next was not well understood.

Jia discusses a mouse study by Song and colleagues that tracked brown fat over a fast. The tissue did not simply burn more fuel as more arrived. After a short early phase of breaking down its own stores, it began to store the incoming fuel instead. By about 20 hours, it held a large pool of stored fat. The commentary explains why storing, rather than burning, may help the whole body manage a long fast.

Catalog record

CREATORWentong Jia
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE12 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13677024

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