Decompressive craniectomy in adults with moderate to severe traumatic brain injury: A systematic review and meta-analysis of randomised controlled trials

Marwan Bouras, Frédérique Lamothe-Boucher, Jihad Abou Jamous, Paule Lessard Bonaventure, Antoine Ouellet, Olivier Costerousse, Charles Francoeur, Ryan Zarychanski, Shane W English, Michael Verret, François Lauzier, Alexis F Turgeon · 2026

Read Decompressive craniectomy in adults with moderate to severe traumatic brain injury: A systematic review and meta-analysis of randomised controlled trials by Marwan Bouras, Frédérique Lamothe-Boucher, Jihad Abou Jamous, Paule Lessard Bonaventure, Antoine Ouellet, Olivier Costerousse, Charles Francoeur, Ryan Zarychanski, Shane W English, Michael Verret, François Lauzier, Alexis F Turgeon (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13676264.txt.

Description

Marwan Bouras and co-authors present a 2026 combined review of trials on a skull surgery for severe brain injury. The operation removes part of the skull to ease pressure inside the head. The team asked how it affects recovery, death rates, and quality of life in adults.

The reviewers searched five major sources for randomized trials, through August 2026. Eligible trials compared the surgery with drug care or other surgical care. Two reviewers pulled data on their own and checked each trial for bias with a standard tool. Pooling only randomized trials gives the fairest test of a risky operation. The results can help doctors and families weigh a last-resort step with very high stakes.

Catalog record

CREATORMarwan Bouras, Frédérique Lamothe-Boucher, Jihad Abou Jamous, Paule Lessard Bonaventure, Antoine Ouellet, Olivier Costerousse, Charles Francoeur, Ryan Zarychanski, Shane W English, Michael Verret, François Lauzier, Alexis F Turgeon
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13676264

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