Projected Impact of LDL-C and HbA1c Control on Cardiovascular Outcomes in ASCVD and Diabetes
Hridhay Karthikeyan, Wenjun Fan, Ran Jin, Nafeesa Dhalwani, Lisa Head, Nathan D. Wong · 2026
Read Projected Impact of LDL-C and HbA1c Control on Cardiovascular Outcomes in ASCVD and Diabetes by Hridhay Karthikeyan, Wenjun Fan, Ran Jin, Nafeesa Dhalwani, Lisa Head, Nathan D. Wong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13676218.txt.
Description
Six researchers project how much heart risk control could prevent events in Americans with artery disease and diabetes in a paper from 2026. They used national survey data weighted to represent about 1.7 million adults. A standard risk score estimated three-year event risk at current cholesterol, blood sugar, and weight levels. The team then recalculated risk under guideline targets for each factor.
Lowering bad cholesterol to the first target cut projected risk by about eighteen percent. A stricter target prevented more events. Adding blood sugar control raised the benefit further. Adding weight loss gave the largest total gain, near thirty-seven percent. The authors conclude cholesterol control alone helps most, but full control helps more.
Catalog record
| CREATOR | Hridhay Karthikeyan, Wenjun Fan, Ran Jin, Nafeesa Dhalwani, Lisa Head, Nathan D. Wong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |