Prolactinoma-associated headache: Clinical and radiological correlates and long-term outcomes
Lukas Andereggen, Christoph Schankin, Philipp Schuetz, Andrea Stieger, Markus M Luedi, Atila Cihan, Michel Roethlisberger, Luigi Mariani, Jürgen Beck, Emanuel Christ · 2026
Read Prolactinoma-associated headache: Clinical and radiological correlates and long-term outcomes by Lukas Andereggen, Christoph Schankin, Philipp Schuetz, Andrea Stieger, Markus M Luedi, Atila Cihan, Michel Roethlisberger, Luigi Mariani, Jürgen Beck, Emanuel Christ (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13675293.txt.
Description
Lukas Andereggen led a 2026 study of headache in prolactinoma patients, asking what drives it and whether upfront medical or surgical treatment relieves it better over the long term. Headache is common with these prolactin-secreting pituitary tumors, yet its determinants and lasting outcomes by first treatment were poorly documented. The team reviewed 145 patients at a tertiary center, tracking headache, hormone levels, tumor size, and cavernous sinus involvement over a median of eighty months.
At diagnosis, 42 patients, or 28.9 percent, had prolactinoma-associated headache. Those patients tended to be older and male, and more often had large tumors with cavernous sinus involvement. That involvement emerged as the only independent predictor, while prolactin levels alone did not predict headache. Headache prevalence fell to 2.8 percent over follow-up, with durable relief after both dopamine agonist therapy and transsphenoidal surgery and no significant difference between them.
Catalog record
| CREATOR | Lukas Andereggen, Christoph Schankin, Philipp Schuetz, Andrea Stieger, Markus M Luedi, Atila Cihan, Michel Roethlisberger, Luigi Mariani, Jürgen Beck, Emanuel Christ |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |