Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Saurabh Joshi, Matthew B Baker, Dominik Schauenburg · 2026
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Description
Saurabh Joshi, Matthew Baker, and Dominik Schauenburg wrote this 2026 review on smart materials that react to several signals at once for regenerative medicine. Healing tissue needs scaffolds and delivery systems that adapt as conditions change. Dynamic covalent chemistry offers bonds that hold firm yet can swap partners, giving materials self-healing and response.
Most designs so far answer a single trigger, such as acidity or enzymes. Real tissue sends mechanical, chemical, and biological cues together, so one-trigger materials behave unpredictably inside the body. The review surveys the reversible bond types in use and how teams combine them. Mixed chemistries, multi-part networks, and layered structures can tune stiffness, relaxation, breakdown, and cell support. The authors close with the gaps blocking clinical use.
Catalog record
| CREATOR | Saurabh Joshi, Matthew B Baker, Dominik Schauenburg |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 108 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |