Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li · 2026
Read Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception by Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13672681.txt.
Description
Cancer that seems gone can return years later, fed by tumor cells that lie dormant. Shih-Hsuan Cheng and co-authors review that problem for cancers of the female reproductive system in a 2026 article. They organize dormancy into entry, maintenance, and awakening, while noting that solid proof of that sequence exists mainly for ovarian cancer.
The review surveys how sleeping cells survive: managing chemical stress, reshaping their energy systems, hiding from the immune system, and leaning on surrounding tissue. It weighs two strategies against them. One would block the wake-up signals to prolong the quiet years. The other would shift the cells' state and then strike with matched treatment. The authors also propose tracking residual disease with blood tests and cell profiling to guide such interception.
Catalog record
| CREATOR | Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 93 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |