The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression
Dario Kohlbrenner, Abdallah Ghaith, Joey Fournier, Charles Khouri, Antonin Bordas, Samarmar Chacaroun, Monique Mendelson, Patrice Flore, Mathieu Marillier, Julien Brugniaux, Jean-Louis Pépin, Renaud Tamisier, Samuel Verges · 2026
Read The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression by Dario Kohlbrenner, Abdallah Ghaith, Joey Fournier, Charles Khouri, Antonin Bordas, Samarmar Chacaroun, Monique Mendelson, Patrice Flore, Mathieu Marillier, Julien Brugniaux, Jean-Louis Pépin, Renaud Tamisier, Samuel Verges (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13672411.txt.
Description
Dario Kohlbrenner and colleagues pool sixty-two trials on training and living in thin air, in this meta-analysis from twenty twenty-six. Intermittent hypoxia comes in three fashions: live high and train low, live low and train high, or passive exposure. Over thirteen hundred healthy participants fed the verdict on maximal oxygen uptake.
The fashions sorted by audience. Living high and training low raised aerobic capacity significantly in athletes, but not detectably in non-athletes. Training high and passive conditioning showed the mirror image: real gains in non-athletes, none proven in athletes. Statistical digging found the dose matters: severity, duration, and frequency of the oxygen shortage all scaled the response. The authors advise prescribing hypoxia like a drug, matched to the population, not as a generic altitude blessing.
Catalog record
| CREATOR | Dario Kohlbrenner, Abdallah Ghaith, Joey Fournier, Charles Khouri, Antonin Bordas, Samarmar Chacaroun, Monique Mendelson, Patrice Flore, Mathieu Marillier, Julien Brugniaux, Jean-Louis Pépin, Renaud Tamisier, Samuel Verges |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |