Multi-level transcriptional control of specific macrophage responses

Alexandra Drakaki, Josje M A Huisman, Marten A Hoeksema · 2026

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Description

Macrophages can adopt diverse functional states in response to environmental cues, a process that is fundamentally controlled at the level of transcriptional regulation. In this review, we outline a hierarchical framework of transcription factor activity that underpins macrophage identity and activation. Firstly, lineage-determining transcription factors establish the cell-type-specific chromatin landscape during development.

Catalog record

CREATORAlexandra Drakaki, Josje M A Huisman, Marten A Hoeksema
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE89 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13672315

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