Comparison of Preservative-Free and Preserved Latanoprost in Primary Open-Angle Glaucoma: A Randomized Cross-Over Study
Ji Heon Lee, Kwanghyun Lee, Jong Woon Park · 2026
Read Comparison of Preservative-Free and Preserved Latanoprost in Primary Open-Angle Glaucoma: A Randomized Cross-Over Study by Ji Heon Lee, Kwanghyun Lee, Jong Woon Park (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13671866.txt.
Description
Ji Heon Lee led a 2026 randomized cross-over study comparing preservative-free latanoprost with preserved latanoprost in primary open-angle glaucoma. Eye drops for glaucoma usually carry preservatives to prevent contamination, yet the preservative can damage the eye surface, driving discomfort and dropout that worsen pressure control. The team enrolled twenty-nine patients, giving each drop for two months before switching to the other, and tracking pressure, tear film, staining, and symptoms.
Both drops lowered pressure by similar amounts. Preserved drops, however, shortened tear break-up time and worsened eye-surface staining, while preservative-free drops held tear stability steady and improved staining. Burning, stinging, and itching were markedly lower without it, and patients switching from preserved to plain drops improved in burning and light sensitivity.
Catalog record
| CREATOR | Ji Heon Lee, Kwanghyun Lee, Jong Woon Park |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |