Metal Hypersensitivity Reactions Following Spinal Implants

Joseph Abbo, Jacob Thomas, Christian Stipho, Erik Nakken, Rakesh Patel, Joshua D. Piche, IIyas Aleem · 2026

Read Metal Hypersensitivity Reactions Following Spinal Implants by Joseph Abbo, Jacob Thomas, Christian Stipho, Erik Nakken, Rakesh Patel, Joshua D. Piche, IIyas Aleem (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13668027.txt.

Description

Joseph Abbo and co-authors reviewed metal allergy after spinal implant surgery in 2026. Such reactions are rare but can imitate infection or loose hardware, making them hard to spot. Guidance rests mostly on case reports, so the team gathered them systematically across three databases.

Fifteen studies covering nineteen patients qualified. Lasting pain was the commonest sign, and over two-fifths had skin changes. Allergy was confirmed by patch or blood tests in just over half; the rest were judged clinically. Onset ranged from right after surgery to fifteen years later. Removing or revising the hardware helped most patients with reported outcomes. The authors urge considering allergy when standard causes are excluded.

Catalog record

CREATORJoseph Abbo, Jacob Thomas, Christian Stipho, Erik Nakken, Rakesh Patel, Joshua D. Piche, IIyas Aleem
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13668027

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