A Two-Tier Patient-Based Real-Time Quality Control Program Integrating K-Means Department Stratification and Inter-Instrument Ratios Improves Detection of Small Systematic Errors in Creatinine Testing
Xuemei Wei, Ziqing Jiang, Jingzhu Nan, Zefeng Yan, Zhu Lin, Rong Li, Jie Feng, Yanhong Gao · 2026
Read A Two-Tier Patient-Based Real-Time Quality Control Program Integrating K-Means Department Stratification and Inter-Instrument Ratios Improves Detection of Small Systematic Errors in Creatinine Testing by Xuemei Wei, Ziqing Jiang, Jingzhu Nan, Zefeng Yan, Zhu Lin, Rong Li, Jie Feng, Yanhong Gao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13664551.txt.
Description
Xuemei Wei and co-authors validate a two-tier quality control scheme that watches lab test errors in real time, in a study from two thousand twenty-six. The scheme tracks creatinine results from patients rather than from control samples alone. Nearly three hundred eighty-five thousand cases from three machines fed the build.
Departments were grouped by result patterns, keeping the low-mean group. Ratios between machines formed the second watch tier. Planted small errors were caught far more often than by the standard method, and faster, though false alarms rose. Single-machine checks showed both tiers add value. The authors offer the frame to multi-machine labs.
Catalog record
| CREATOR | Xuemei Wei, Ziqing Jiang, Jingzhu Nan, Zefeng Yan, Zhu Lin, Rong Li, Jie Feng, Yanhong Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |