PRAME predicting outcome in uveal melanoma
Sally Owens, Naomi Walsh, Noel Horgan, Patrick Murtagh, Katie Hanratty, Grainne Finegan, Laura Ivers, John Crown, Susan Kennedy · 2026
Read PRAME predicting outcome in uveal melanoma by Sally Owens, Naomi Walsh, Noel Horgan, Patrick Murtagh, Katie Hanratty, Grainne Finegan, Laura Ivers, John Crown, Susan Kennedy (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13662831.txt.
Description
Sally Owens and co-authors test a protein marker in eye cancer in a 2026 study. The cancer is uveal melanoma, the most common eye tumor in adults. It spreads to other organs in about half of patients. The marker, called PRAME, may flag tumors that are more likely to spread, but most past work used gene tests, not standard lab stains.
The team stained tumor samples from a large group of patients and tracked survival. Stains on full tumor slices linked the marker to much shorter time before spread. Stains on tiny tissue cores gave weaker results. The study supports the marker as a warning sign when full slices are used.
Catalog record
| CREATOR | Sally Owens, Naomi Walsh, Noel Horgan, Patrick Murtagh, Katie Hanratty, Grainne Finegan, Laura Ivers, John Crown, Susan Kennedy |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |