Fracture and Vertebral Augmentation Utilization Following Androgen Deprivation Therapy in Men With Prostate Cancer: A Propensity Score–matched Cohort Study

Taha Taka, Carson Cummings, Sarah Meng, Andrew Miner, Graydon Dietrich, David Shin, Trupti Trivedi, Rory Goodwin, William Richardson, Olumide Danisa · 2026

Read Fracture and Vertebral Augmentation Utilization Following Androgen Deprivation Therapy in Men With Prostate Cancer: A Propensity Score–matched Cohort Study by Taha Taka, Carson Cummings, Sarah Meng, Andrew Miner, Graydon Dietrich, David Shin, Trupti Trivedi, Rory Goodwin, William Richardson, Olumide Danisa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13661820.txt.

Description

Taha Taka and co-authors count spine fractures after hormone-blocking therapy for prostate cancer. The treatment starves tumors but also bone, thinning vertebrae until they crumple. Matching treated men one-to-one with untreated patients, 122,511 per side, the team tracked compression fractures and the cement procedures that repair them over five years.

Fractures ran 1.95 percent in treated men against 1.29 percent in controls, a hazard ratio of 1.49, roughly one extra fracture per 143 men treated. Among those who fractured, cement augmentation was also half again as common after hormone therapy, while bigger fusion surgery and dependency rates matched. The authors press for bone screening and protection from day one of therapy.

Catalog record

CREATORTaha Taka, Carson Cummings, Sarah Meng, Andrew Miner, Graydon Dietrich, David Shin, Trupti Trivedi, Rory Goodwin, William Richardson, Olumide Danisa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13661820

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