Species-selective plasma metabolism drives lysophosphatidylcholine depletion after cardiac arrest
Muhammad Shoaib, Jacob S. Kazmi, Mitsuaki Nishikimi, Rishabh C. Choudhary, Jaekyung Cho, Tai Yin, Parmeshar Singh, Cyrus E. Kuschner, Jaewoo Choi, Blanca B. Espin, Lance B. Becker, Li Ma, Junhwan Kim · 2026
Read Species-selective plasma metabolism drives lysophosphatidylcholine depletion after cardiac arrest by Muhammad Shoaib, Jacob S. Kazmi, Mitsuaki Nishikimi, Rishabh C. Choudhary, Jaekyung Cho, Tai Yin, Parmeshar Singh, Cyrus E. Kuschner, Jaewoo Choi, Blanca B. Espin, Lance B. Becker, Li Ma, Junhwan Kim (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13661218.txt.
Description
A team led by Muhammad Shoaib asks why a key blood fat fades so fast after cardiac arrest, in this study from twenty twenty-six. The fat is lysophosphatidylcholine, or LPC, and past work showed that giving more of it helps patients and animals survive. What no one knew was where the LPC goes.
With a tagged form of LPC, the team tracked its loss in the blood after arrest. The fall was not even: LPC types with chains rich in double bonds dropped the most. The cause was fast breakdown in the blood itself, not lower output from the liver or uptake by tissues. Changes in LPC also tracked with changes in related fats, which hints at a wide upset in blood fat balance. Care, the authors argue, must either slow this removal or top LPC back up.
Catalog record
| CREATOR | Muhammad Shoaib, Jacob S. Kazmi, Mitsuaki Nishikimi, Rishabh C. Choudhary, Jaekyung Cho, Tai Yin, Parmeshar Singh, Cyrus E. Kuschner, Jaewoo Choi, Blanca B. Espin, Lance B. Becker, Li Ma, Junhwan Kim |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |