A national spatial prioritisation framework for the targeted expansion of essential sickle cell disease services across health-facility catchments in Uganda

George Paasi, Grace Ndeezi, Ruth Namazzi, Ezekiel Mupere, Ian Guyton Munabi, Sarah Kiguli, Richard Idro, Peter Olupot-Olupot · 2026

Read A national spatial prioritisation framework for the targeted expansion of essential sickle cell disease services across health-facility catchments in Uganda by George Paasi, Grace Ndeezi, Ruth Namazzi, Ezekiel Mupere, Ian Guyton Munabi, Sarah Kiguli, Richard Idro, Peter Olupot-Olupot (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13660151.txt.

Description

George Paasi and co-authors build a national map to guide where Uganda should expand sickle cell disease services first. The inherited blood disorder causes heavy childhood illness and early death in Africa, yet screening and treatment remain patchy. The team linked 280 higher-level public facilities to the populations within an hour's modeled travel.

Each zone got scores combining local genetic risk, malaria rates, missing services, and social vulnerability. Over forty percent of zones reported none of the four key services, which are newborn screening, a key drug, transfusion, and specialist clinics. Nearly three quarters had at most one. Priority ran highest in northern, north-eastern, and eastern Uganda. The framework gives planners a transparent way to aim scarce resources where need and gaps are greatest.

Catalog record

CREATORGeorge Paasi, Grace Ndeezi, Ruth Namazzi, Ezekiel Mupere, Ian Guyton Munabi, Sarah Kiguli, Richard Idro, Peter Olupot-Olupot
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE90 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13660151

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