Biosynthesis and analytics of specialized pro-resolving mediators: facts and faults
Nils Helge Schebb, Hartmut Kühn, Nadja Kampschulte, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Hans-Erik Claesson, Karsten H. Weylandt, Nadine Rohwer, Meike J. Saul, Eugen Proschak, Bernhard Brüne, Ulrike Garscha, Thorsten J. Maier, Paola Patrignani, Miguel A. Gijón, Francisco J. Scho · 2026
Read Biosynthesis and analytics of specialized pro-resolving mediators: facts and faults by Nils Helge Schebb, Hartmut Kühn, Nadja Kampschulte, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Hans-Erik Claesson, Karsten H. Weylandt, Nadine Rohwer, Meike J. Saul, Eugen Proschak, Bernhard Brüne, Ulrike Garscha, Thorsten J. Maier, Paola Patrignani, Miguel A. Gijón, Francisco J. Scho (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13658875.txt.
Description
Nils Helge Schebb and co-authors wrote a 2026 review that questions a fashionable family of inflammation-resolving molecules. These molecules, called specialized pro-resolving mediators, are said to switch inflammation off. Drug studies with lab-made versions support real effects. But the review asks whether the body actually makes them in meaningful amounts.
The authors check the enzymes said to build the molecules and the receptors said to receive them. Both lines of evidence raise doubt. They also audit reports of the molecules in body samples. Many used methods that miss community standards, or antibody tests too loose to prove presence. Some readings may be artifacts from air damage to fats. The review urges stricter proof before the field builds further on these claims.
Catalog record
| CREATOR | Nils Helge Schebb, Hartmut Kühn, Nadja Kampschulte, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Hans-Erik Claesson, Karsten H. Weylandt, Nadine Rohwer, Meike J. Saul, Eugen Proschak, Bernhard Brüne, Ulrike Garscha, Thorsten J. Maier, Paola Patrignani, Miguel A. Gijón, Francisco J. Scho |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |