Targeted AAV gene therapy for neuroblastoma via direct capsid-antibody coupling

Mirko Luoni, Stefano Parracino, Serena G Giannelli, Francesca Morosi, Elisa Ventura, Agostina Di Pizio, Sharon Muggeo, Angelo Iannielli, Silvia Sicardi, Tamara Canu, Tommaso Russo, Antonio Esposito, Ubaldo Del Carro, Fabio Pastorino, Vania Broccoli · 2026

Read Targeted AAV gene therapy for neuroblastoma via direct capsid-antibody coupling by Mirko Luoni, Stefano Parracino, Serena G Giannelli, Francesca Morosi, Elisa Ventura, Agostina Di Pizio, Sharon Muggeo, Angelo Iannielli, Silvia Sicardi, Tamara Canu, Tommaso Russo, Antonio Esposito, Ubaldo Del Carro, Fabio Pastorino, Vania Broccoli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13658805.txt.

Description

Mirko Luoni and co-authors stitch a guide head to a tame germ shell to send gene fare just to nerve growth cells. Germ shells are safe and broad, yet that breadth spills fare to sound flesh. Their 2026 craft locks a tag on the shell; a cut guide head with the same tag's mate clicks on at set dose. The shell is first dulled to its old food pull.

In mouse growth runs, the stitched shell reads growth cells and spares the liver whole. A kill gene sent by it slows growths and lengthens life. With stock dose drugs in tow, cures land in the runs. Click-on heads make shells a gen­eral aim craft.

Catalog record

CREATORMirko Luoni, Stefano Parracino, Serena G Giannelli, Francesca Morosi, Elisa Ventura, Agostina Di Pizio, Sharon Muggeo, Angelo Iannielli, Silvia Sicardi, Tamara Canu, Tommaso Russo, Antonio Esposito, Ubaldo Del Carro, Fabio Pastorino, Vania Broccoli
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE133 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13658805

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