From localized to long-range: functional connectivity alterations in mild to moderate chronic low back pain patients
Han-Jun Hu, Luo-Yu Wang, Jia-Yi Deng, Yi Lin, Zhong-Xiang Ding, Xue Tang, Yi-Di Zhu, Xiu-Hong Ge, Han Zhang, Liang Yu, Li-Qing Zhang · 2026
Read From localized to long-range: functional connectivity alterations in mild to moderate chronic low back pain patients by Han-Jun Hu, Luo-Yu Wang, Jia-Yi Deng, Yi Lin, Zhong-Xiang Ding, Xue Tang, Yi-Di Zhu, Xiu-Hong Ge, Han Zhang, Liang Yu, Li-Qing Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13654137.txt.
Description
Han-Jun Hu and colleagues used brain scans to study how mild to moderate chronic low back pain affects the brain. Pain that lasts can change how brain areas work together. The team measured both local activity and long-range links between areas. They also checked how the scan results tied to pain and mood scores.
Fifty-five patients and thirty-nine healthy adults had resting brain scans. The patients showed weaker local activity in a part of the cerebellum at the back of the brain. Wider links between regions also differed from the healthy group. Some of these changes tracked with pain levels, anxiety, depression, and sleep quality. The work maps how even mild back pain leaves a mark on brain networks.
Catalog record
| CREATOR | Han-Jun Hu, Luo-Yu Wang, Jia-Yi Deng, Yi Lin, Zhong-Xiang Ding, Xue Tang, Yi-Di Zhu, Xiu-Hong Ge, Han Zhang, Liang Yu, Li-Qing Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |