Precision gene editing technology to modulate genes in oral diseases: Therapeutic applications and delivery strategies

Yihan Wang, Xuesong Li, Chunpeng Liu, Bing He, Yiming Liu, Qingyan Liu, Chenyu Liu, Daiyun Chen, Shufang Wang, Lin Zhang · 2026

Read Precision gene editing technology to modulate genes in oral diseases: Therapeutic applications and delivery strategies by Yihan Wang, Xuesong Li, Chunpeng Liu, Bing He, Yiming Liu, Qingyan Liu, Chenyu Liu, Daiyun Chen, Shufang Wang, Lin Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13651494.txt.

Description

Yihan Wang and co-authors reviewed in 2026 how precise gene editing might treat diseases of the mouth. Such diseases affect billions of people and are linked to heart disease, diabetes, and joint disease. Normal care relies on cleaning, scraping, and germ-fighting drugs, which have clear limits.

Editing tools, chiefly CRISPR-Cas9, can change set genes and shift how cells behave. The review covers uses for tooth decay, mouth cancer, and defects of the jaw and face bones. It also weighs ways to deliver the tools, from physical methods to tiny carriers and gels. Most proof is still early, and safe delivery plus off-target change remain major hurdles.

Catalog record

CREATORYihan Wang, Xuesong Li, Chunpeng Liu, Bing He, Yiming Liu, Qingyan Liu, Chenyu Liu, Daiyun Chen, Shufang Wang, Lin Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE68 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13651494

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