Reproducibility of diffusion, shape, and connectivity metrics across scanners: Implications for multi-site tractography
Sachit Anand, Fang-Cheng Yeh, Siva Venkadesh · 2026
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Description
Brain scans pooled across hospitals carry a hidden flaw: each scanner bends the numbers in its own way. Sachit Anand, Fang-Cheng Yeh, and Siva Venkadesh compared three families of tract measures for that flaw in a 2026 study. Data came from five people scanned on four scanners across many sessions. The families cover water spread, tract shape, and tract links in the brain's wiring.
Shape measures proved the steadiest across scanners, with links next and water spread last. A standard fix method lifted all three families but did not close the gap. When data were squeezed into fewer numbers, link measures jumped ahead of the rest. The authors say the choice of measure family matters even after fixes. Multi-site studies should plan for that from the start.
Catalog record
| CREATOR | Sachit Anand, Fang-Cheng Yeh, Siva Venkadesh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |