Investigating the Impact of Curcumin on the Methylation of DNMT1, CDH1, SMG1, and WT1 Genes in the MIAPaCa2 Cell Line Using High-Resolution Melting Analysis Compared to Methylation-Specific PCR
Shaghayegh Mousavi, Mehdi Azad, Neda Karami Chermahini, Abdolmabood Momeni · 2026
Read Investigating the Impact of Curcumin on the Methylation of DNMT1, CDH1, SMG1, and WT1 Genes in the MIAPaCa2 Cell Line Using High-Resolution Melting Analysis Compared to Methylation-Specific PCR by Shaghayegh Mousavi, Mehdi Azad, Neda Karami Chermahini, Abdolmabood Momeni (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13651431.txt.
Description
Shaghayegh Mousavi, Mehdi Azad, Neda Karami Chermahini, and Abdolmabood Momeni wrote a 2026 paper on turmeric's active compound and cancer genes. Curcumin, the yellow spice extract, can change how genes are switched off by chemical tags called methylation. The team tested its effect on four genes in pancreatic cancer cells grown in dishes.
Cells were treated with five doses of curcumin for up to three days. The team then measured gene tagging with two methods: a classic targeted test and a melting method that gives amounts. Comparing the two methods matters because the newer one is faster but less proven. Work like this explores whether a food compound could one day support cancer care, and checks the tools used to claim it.
Catalog record
| CREATOR | Shaghayegh Mousavi, Mehdi Azad, Neda Karami Chermahini, Abdolmabood Momeni |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |