pH-modulating binary hydrogen-bonded organic frameworks accelerate diabetic wound healing
Junpeng Sun, Xiang Sun, Mei Xia, Qianjun Xiao, Kaikai Ma, Zike Liao, Guanglai Mo, Xiaoying Li, Luying Lai, Haihao Huang, Chunhui Cui, Peng Li, Xiaopin Duan, Jisheng Xiao · 2026
Read pH-modulating binary hydrogen-bonded organic frameworks accelerate diabetic wound healing by Junpeng Sun, Xiang Sun, Mei Xia, Qianjun Xiao, Kaikai Ma, Zike Liao, Guanglai Mo, Xiaoying Li, Luying Lai, Haihao Huang, Chunhui Cui, Peng Li, Xiaopin Duan, Jisheng Xiao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13651154.txt.
Description
Junpeng Sun and thirteen co-authors, in 2026, coat a wound fabric with a crystalline framework built to steer the acidity of diabetic foot ulcers. Those wounds stall because their environment stays too alkaline and infection-prone. Healthy healing needs a moving target: acidic early to fight bacteria, then gentler conditions for skin cells to rebuild.
The framework, built from hydrogen-bonded organic units, guides the wound through a near-neutral, weakly acidic, then near-neutral sequence while its light-activated chemistry suppresses infection. Bench tests showed strong blood-clotting performance, high moisture transmission, safety, and long-term stability. The coating also managed wound fluid and calmed inflammation in the team's testing. The authors present the material as a combined plan that modulates acidity, fights infection, encourages vessel growth, and boosts collagen, aiming squarely at one of diabetes care's most stubborn complications.
Catalog record
| CREATOR | Junpeng Sun, Xiang Sun, Mei Xia, Qianjun Xiao, Kaikai Ma, Zike Liao, Guanglai Mo, Xiaoying Li, Luying Lai, Haihao Huang, Chunhui Cui, Peng Li, Xiaopin Duan, Jisheng Xiao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 103744 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |