Chitosan in regenerative medicine: a translational perspective on biomaterial design

Adrianna Banach-Kopeć, Lisa Gugler, Karol Staszczyk, Szymon Mania, Agnes S. Klar, Robert Tylingo · 2026

Read Chitosan in regenerative medicine: a translational perspective on biomaterial design by Adrianna Banach-Kopeć, Lisa Gugler, Karol Staszczyk, Szymon Mania, Agnes S. Klar, Robert Tylingo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13650546.txt.

Description

Adrianna Banach-Kopeć and five colleagues review chitosan, a sugar-based polymer from shells and fungi, as a building material for regenerative medicine. Its charge, solubility, and breakdown rate can all be tuned, which makes it attractive for scaffolds, gels, coatings, and printing inks meant to help tissue regrow.

That tunability is also the problem: products all sold as chitosan differ widely in chemistry, purity, contamination, and sterilization history, so results rarely transfer cleanly. The authors walk through sources, extraction routes, medical-grade purity demands, germ-fighting behavior, and combinations with growth factors, drugs, cells, and cell-derived vesicles. Their verdict is that chitosan is neither automatically body-friendly nor automatically germ-killing; performance depends on the exact formulation and use. They call for standardized reporting of key chemical measures and manufacturing that regulators can actually verify.

Catalog record

CREATORAdrianna Banach-Kopeć, Lisa Gugler, Karol Staszczyk, Szymon Mania, Agnes S. Klar, Robert Tylingo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE112 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13650546

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