MAFLD and impaired bone formation in children: association with reduced serum LCAT
Lingyan Zhu, Lin Xu, Lanshu Yang, Baolan Sun, Weixia Yang · 2026
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Description
Lingyan Zhu and four colleagues checked bone growth signs and a fat-handling enzyme in children with fatty liver disease tied to poor metabolic health. The study held 127 children aged six to 14: healthy controls, children with obesity but a clean liver, and children with the liver disease.
The enzyme, called LCAT, ran highest in controls and lowest in the liver disease group. A bone growth marker sat in the low range for near nine in ten children with liver disease, a far higher share than in the other groups. In adjusted models, liver disease itself and older age tied to low bone growth status, while the enzyme did not stand alone. The authors call the enzyme a linked marker, not a proven cause.
Catalog record
| CREATOR | Lingyan Zhu, Lin Xu, Lanshu Yang, Baolan Sun, Weixia Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |