Assessing the threat of artemisinin resistance: seasonal and ecological patterns of PfKelch13 mutation distribution in malaria-endemic communities in Ghana
Mavis Puopelle Dakorah, Enoch Aninagyei, Godwin Adzakpah, Juliana Attoh, Isaac Tukwarlba, Desmond Omane Acheampong · 2026
Read Assessing the threat of artemisinin resistance: seasonal and ecological patterns of PfKelch13 mutation distribution in malaria-endemic communities in Ghana by Mavis Puopelle Dakorah, Enoch Aninagyei, Godwin Adzakpah, Juliana Attoh, Isaac Tukwarlba, Desmond Omane Acheampong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13649500.txt.
Description
Mavis Puopelle Dakorah and five colleagues mapped gene changes tied to malaria drug resistance across communities in Ghana's Central Region. Resistance to the main drug family would threaten hard-won gains against malaria. The team sequenced blood samples from 358 people and read one key gene in the malaria parasite.
The normal form of the gene still ruled in most places, but mutant forms were rich and varied. More than a hundred samples carried one change, dozens carried two, and a few carried three or four. Neither season nor broad land zone explained the pattern, yet the home district did. Known strong resistance markers stayed rare. The authors urge fine-grained watch work to catch spread early.
Catalog record
| CREATOR | Mavis Puopelle Dakorah, Enoch Aninagyei, Godwin Adzakpah, Juliana Attoh, Isaac Tukwarlba, Desmond Omane Acheampong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |