Clinical features and management of medication-induced persistent corneal epithelial defects due to topical ophthalmic medications
Shunrong Luo, Nuozhou Wu, Yuan Lin, Huping Wu · 2026
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Description
Shunrong Luo and three colleagues studied eye surface wounds that fail to heal because of the very drops used to treat the eyes. They reviewed 60 cases seen from 2020 to 2024 and tracked which drops were used, how often, and for how long.
Damage grew worse with more drugs used at once, more doses per day, and longer use. Most cases were judged probable drug reactions, and many were severe. Once harmful drops were stopped and replaced with gentler, preservative-free ones, most wounds healed within a month. The worst cases also got soft bandage lenses or membrane grafts. Total cure reached over four in five cases with this step-by-step care.
Catalog record
| CREATOR | Shunrong Luo, Nuozhou Wu, Yuan Lin, Huping Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |