Beyond endometrial thickness: platelet-rich plasma and reproductive outcomes in recurrent implantation failure following euploid embryo transfer

Flavia Costanzi, Ermanno Greco, Maria Teresa Varricchio, Ilaria Listorti, Sara Fusco, Gianluca Dani, Giuseppe Grimaldi, Maria Alba Stigliano, Pierfrancesco Greco · 2026

Read Beyond endometrial thickness: platelet-rich plasma and reproductive outcomes in recurrent implantation failure following euploid embryo transfer by Flavia Costanzi, Ermanno Greco, Maria Teresa Varricchio, Ilaria Listorti, Sara Fusco, Gianluca Dani, Giuseppe Grimaldi, Maria Alba Stigliano, Pierfrancesco Greco (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13649411.txt.

Description

Flavia Costanzi and eight colleagues tested whether platelet-rich plasma, made from a woman's own blood, helps embryos implant after repeated failures. All women in the study had a normal womb lining width, so low width could not explain their losses. Two hundred thirty women took part at one centre from late 2023, with 110 choosing the plasma wash and 120 serving as controls.

Pregnancy rates were far higher in the plasma group, and the gap held after the team adjusted for other factors. Live birth rates were higher too. Since women chose their own group rather than being assigned by chance, bias may remain. The authors call for firmer trials to confirm the benefit.

Catalog record

CREATORFlavia Costanzi, Ermanno Greco, Maria Teresa Varricchio, Ilaria Listorti, Sara Fusco, Gianluca Dani, Giuseppe Grimaldi, Maria Alba Stigliano, Pierfrancesco Greco
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13649411

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