Association of a routine dexmedetomidine-remifentanil anesthetic strategy with POD3 morning cortisol change in older patients undergoing radical esophagectomy

Yuling Yang, Junbiao Chen, Zhicheng Lin, Lisha Yi, Nanye Zhu, Jiangquan Hong, Yimin Lin, Jiabin Li · 2026

Read Association of a routine dexmedetomidine-remifentanil anesthetic strategy with POD3 morning cortisol change in older patients undergoing radical esophagectomy by Yuling Yang, Junbiao Chen, Zhicheng Lin, Lisha Yi, Nanye Zhu, Jiangquan Hong, Yimin Lin, Jiabin Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13649391.txt.

Description

Yuling Yang and seven colleagues asked if a paired drug plan for sleep during surgery calms the stress response in older patients. The surgery removed part of the food pipe to treat cancer, a major operation. The team looked back at records from 2023 to 2025 at one centre and matched three drug plans in groups of 100 patients each.

The paired plan, using both drugs, showed the smallest rise in the stress hormone cortisol by day three. Pain scores in the first day were also lower than with one drug alone. Scores for thinking decline were a bit lower too, but that gap was not firm. The authors want a larger trial before firm claims.

Catalog record

CREATORYuling Yang, Junbiao Chen, Zhicheng Lin, Lisha Yi, Nanye Zhu, Jiangquan Hong, Yimin Lin, Jiabin Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13649391

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